Bloodchief Ascension + Mindcrank is a two card combo that will either drain your opponents life (while feeding your own) or mill them to death with one tiny scratch.

While this is the inspiration for the deck, the combo need not always be present to win.  Bloodghasts tend to annoy with little fear of them dying permanently and the abundant burn spells can help whittle away your opponents life.

Proliferate speeds up your ascension and there is a little card draw in there to help speed you through to those important cards.