BUG: Cut Spiral since the main thing we're wanting to draw are ways to kill PWs and ways to not die anyway.  They usually have 4-5 Forest + 1 Swamp.
-4 Spiral
+1 Tyrant
+3 Trophy

Esper: Cut Spiral since we want every card to be a good Thought Erasure target. 
-2 Ram (-4 on draw)
-2 Cast Down (keep all on draw for Thief and HT)
-4 Spiral
-3 Soot
+1 Tyrant
+3 Thief
+4 Negate
+3 Trophy

Mono Red: Cut top-end for cheaper interactions.  Maybe Tyrant on the play.
-2 Tyrants
-4 Reborn
-1 Spiral
-1 Find
+4 Negate
+2 Moment
+2 Cry

Mono Blue: Cut top-end for cheaper interactions.  Trophy is fine since it's most likely going to draw out Dive Down/Spell Pierce anyway.  Krasis for 2 slows them down enough. 
-2 Tyrants
-4 Reborn
-1 Summit
-2 Contempts
-1 Find
+3 Thief
+3 Trophy
+2 Moment
+2 Cry

Wx Aggro: Cut top-end for cheaper interactions.  Trophy is for Tribunal/Adanto land.
-2 Tyrants
-4 Reborn
+2 Trophy
+2 Moment
+2 Cry

Drakes: Cut top-end for cheaper interactions.  Trophy is fine since it's most likely going to draw out Dive Down/Spell Pierce anyway.
-2 Tyrants
-1 Soot
+3 Trophy

Gates: mostly have to fight the card draw engines (Summit/Explosion).  They usually have 2-5 basics.
-2 Tyrants
-2 Spiral
-3 Cast Down
-3 Soot
+3 Thief
+4 Negate
+3 Trophy

Nexus: Azcanta and Reclamations are priority things to use permission for.  Teferi can be killed after.  They have 1-3 basics.
-2 Tyrants
-2 Reborn
-3 Cast Down
-3 Soot
+3 Thief
+4 Negate
+3 Trophy

Reclamation: fight their Azcanta, Reclamation, and Niv.  Clock ASAP with Tyrants.  Be wary of Star.
-1 Reborn
-4 Contempts
-3 Cast Down
-3 Soot
+1 Tyrant
+3 Thief
+4 Negate
+3 Trophy

Esper Mid: they're a Thought Erasure deck so cut Spiral.  Deal with Thieves and any PW.  Play around Hostage Taker.  They have 1-2 basics.
-2 Tyrants
-4 Spiral
+2 Negate
+2 Trophy
+2 Cry